2006 Schedule (14-1, 9-0)
| Date | Opponent | Location | Result | Additional Info |
| Sept. 2 | Minnesota State | Bearcat Stadium | W, 31-14 | Recap |
| Sept. 9 | No. 10 Nebraska-Omaha | Bearcat Stadium | W, 31-0 | Recap |
| Sept. 16 | Truman* Hickory Stick Game |
Kirksville, Mo. | W, 31-10 | Recap |
| Sept. 23 | Missouri Western* | Bearcat Stadium | W, 24-21 | Recap |
| Sept. 30 | Missouri Southern* | Joplin, Mo. | W, 24-7 | Recap |
| Oct. 7 | Emporia State* | Bearcat Stadium | W, 49-17 | Recap |
| Oct. 14 | Washburn* | Topeka, Kan. | W, 31-26 | Recap |
| Oct. 21 | Fort Hays State* Homecoming |
Bearcat Stadium | W, 59-0 | Recap |
| Oct. 28 | Central Missouri* | Warrensburg, Mo. | W 31-14 | Recap |
| Nov. 4 |
Pittsburg State* |
Kansas City, Mo. | W 41-14 | Recap |
| Nov. 11 | Southwest Baptist* | Bolivar, Mo. | W, 55-9 | Recap |
| Nov. 25 | Midwestern State NCAA Playoffs - Second Round |
Bearcat Stadium | W, 27-0 | Recap |
| Dec. 2 | Chadron State NCAA Playoffs - Quarterfinals |
Bearcat Stadium | W, 28-21 | Recap |
| Dec. 10 | Bloomsburg (Pa.) NCAA Playoffs - Semifinals |
Bearcat Stadium | W, 33-3 | Recap |
| Dec. 16 | Grand Valley State NCAA Championship |
Florence, Ala. | L, 14-17 | Recap |
Home games in bold
