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Northwest Missouri State University

Faculty/Staff Spotlight

July 23, 2010

Dr. Rafiq Islam

Dr. Rafiq Islam, chemistry and physics professor, has been awarded a grant totaling $208,800 over the next three years to continue researching the regulation of the polycystic kidney disease gene. Islam received the funding from the National Institutes of Health (NIH) for his research, titled "Novel Mekk1-p53 Mediated Transcriptional Regulation: Mechanism and Genome Wide Study" through June 30, 2013.

In 2005, NIH awarded Islam $195,000 to support his study on how MEKK1, a mitogenic protein, regulates the polycystic kidney disease (PKD) gene. The NIH award was the first-ever for Northwest. During Islam's research during the previous funding period, his team identified a previously-unknown mechanism in which two independent regulators, MEKK1 and p53, an antitumor protein, come together to regulate the PKD gene.

The additional NIH grant funding will enable Islam to study this new mechanism further. Islam will research how it regulates the PKD gene and whether other genes are regulated by the new mechanism.

For more information, please contact:

Mark Hornickel, Communication Manager | 660.562.1704 | Fax: 660.562.1900

Northwest Missouri State University
215 Administration Building | 800 University Drive | Maryville, MO 64468