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The National Research Act of 1974/1983 (PL 93‑348) dictates that, in order for institutions to be eligible for behavioral or biomedical research grants from federal sources (e.g., The Department of Health and Human Services and its various research institutes), an institutional Review Board (IRB) must be established and maintained to review research involving human subjects. The charge of this IRB is to protect the rights of those subjects participating in such research at this institution. The IRBs review of the applications is guided by the Code of Federal Regulations (Title 45, Part 46), which sets the minimum standards for protection of human subjects.
For more information, view the IRB Purpose