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Northwest Missouri State University


CIE Analytical Laboratory

Overview | Method Developments | Sample Analysis | Specific Services

Overview

The CIE Analytical Laboratory associated with Northwest Missouri State University has a state-of-the-art equipment facility. We can offer contract research and development (R & D) and drug discovery work (Non-GLP and Non-GMP) in the analysis of biological and environmental samples for pharmaceuticals, metabolites/biomarkers, personal care products, chemical, elemental and environmental pollutants, etc. The CIE Analytical Laboratory also analyses samples as per customers’ requests employing their standards and custom methods.

Our in-house professional analytical chemist, Dr. Abdul Mottaleb, has regulatory EPA and non-regulatory laboratories work experience. He has met analytical challenges in separation, method development, method validation and identification of compounds from complex biological and chemical samples.

With our analytical chemist, the CIE Analytical Lab can provide the following analytical/bioanalytical services to customers as per their need that includes:

  • Method development and method validation
  • Samples analysis, detection and identification
  • Standard and custom methods for processing the samples

For analysis or method questions contact:

Dr. M. Abdul Mottaleb, Analytical Chemist
Phone: 660.562.0820
E-mail: mmottal@nwmissouri.edu
Website: Curriculum Vitae

For pricing information contact:

Larry Lee, Director
Phone: 660.562.0823
Email: llee@nwmissouri.edu

Method Development and Method Validation Services

Method developments are always challenging for analysis biological and complex chemical samples. At the CIE Laboratory, we can develop new analytical methodology sharing customer's existing experience or from a minimal amount of information.

Method development and validation include:

Literature Review

  • Literature review to assess the current information for a specific compound of interest
  • Saving time to develop methodology

Setting Up Appropriate Analytical Techniques

We have ample experienced professional analytical chemists capable of extracting compounds from a wide range of samples such as waters, wastewaters, semi-solids and tissues and setting up appropriate techniques. Typically preparation of sample-analysis by chromatography and mass spectrometry, the following steps are commonly used:

  • Liquid/liquid extraction and micro liquid/liquid extraction
  • Solid-phase extraction
  • Centrifugation and clean-up procedure prior to analysis of samples

Sample Analysis, Detection and Identification

We offer chromatography method together with other appropriate instruments (see equipment list on back panel) for complete characterization of the samples. We also analyze the samples as per customers' needs using standard and customized methods with high selectivity, high sensitivity and conventional detection system.

Specific Services

Typically For LC Method

  • Capillary reversed phase and normal phase column chromatography
  • Autosampler injection with partial loop sample injection ability
  • Gradient and isocratic separation
  • Photo-diode array (PDA) detection
  • High sensitivity and selectivity MS/MS detection that has isomer characterization capability

For GC Method

  • Capillary column separation
  • Autosampler injection
  • Full-scan MS detection and NIST library match search ability
  • High selectivity and sensitivity MS/MS detection and has isomer characterization ability
  • Aliquot sample (1 micro-liter) requirement for analysis
  • Purge and trap facility to determine volatile organic compounds (VOC) using EPA 8260 method.

For FTIR Analysis

  • Identification of chemical bonds in a molecule
  • Solids, powders, pastes and polymer samples can be analyzed

For CHNS/O Analyzer

  • Simultaneous analysis of the percentage of carbon (C), hydrogen (H), nitrogen (N) and sulfur (S)
  • Solid, powders and polymeric materials can be analyzed

For Nanoparticle Size Analyzer

  • Determination of submicron particle size
  • Colloids, micelles, paints and pigments, ink and tuners, micro-emulsions and proteins can be analyzed

For UV/VIS Analyzer

  • Fast scanning for characteristics of the molecule or ion
  • Liquid samples are used